Epigenetics and Novel Therapeutic Approaches

Novel Therapeutic Approaches for Neuroblastoma

Glioblastoma Multiforme: Novel Therapeutic Approaches

The current therapy for glioblastoma multiforme involves total surgical resection followed by combination of radiation therapy and temozolomide. Unfortunately, the efficacy for such current therapy is limited, and newer approaches are sorely needed to treat this deadly disease. We have recently described the isolation of bacterial proteins and peptides with anticancer activity. In phase I human...

Therapeutic Approaches of Some Novel Glyoxaline Derivatives

Alka Pradhan , Harshita Goyal , Nazish Khan Dept. of Chemistry, Govt. Motilal Vigyan Mahavidyalaya ,Bhopal Abstract Gloxaline have occupied a unique position in heterocyclic chemistry, and its derivatives have attracted considerable interests in recent years for their versatile properties in chemistry and pharmacology. Gloxaline is nitrogen-containing heterocyclic ring which possesses biologica...

Novel Gene Therapeutic Approaches to Brain Cancer

INTRODUCTION In the United States, approximately 17,000 people per year are diagnosed with brain tumors, the leading cause of death from cancers in children ages 1-15 year (1,2). Gliomas are the most prevalent type of brain tumors in adults, affecting 3.2/100,000 persons/yr in the United States (www.CBTRUS.org). In spite of advances in surgery, chemotherapy, and radiotherapy, the mean survival ...

Novel Therapeutic Approaches for High-Grade Gliomas

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